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Occurs most often at higher doses Can be reduced by starting with a lower dose Some men take anti-nausea medication to prevent this effect Flushing and Warmth Some men experience a sudden warming sensation, facial flushing, or skin redness shortly after injecting PT-141

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Heterogeneity was assessed using the I statistic, where values above 50% were interpreted as indicating moderate to high heterogeneity, alongside Cochranes Q test to evaluate the statistical significance of between-study variation

Including such studies could lead to misleading conclusions about GSHs efficacy, as its potential benefits in NAFLD may not apply to more advanced or non-metabolic liver diseases